Pipeline

Project*

Payload

Target

Profile

Advantage

Pre-Clinical

Phase 1

AT-03 AxcynDOT CLDN6 First-in-Class Tumor-specific, clinically validated target

AT-06 AxcynDOT or DuXd DLL3 x SEZ6 Bispecific ADC SCLC
AT-01 AxcynDOT and DuXd ROR1 Dual Payload Efficacy Synergy for low-expression targets
AT-00 AxcynDOT HER2 Best-in-Class Overcome resistance
AT-04 Duxd ALPP/ALPPL2 First-in-Class PDAC – panRAS inhibitor combination

*Click on the project code to learn more about Axcynsis’s program.